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Research Projects


Efficacy and Mechanisms of Combined Aerobic Exercise and Cognitive Training in MCI (The ACT Trial)

Dates: 9/15/2017 - 5/31/2022


Role: Mary Carey, PhD, RN, FAHA, FAAN : Co-Investigator
Principal Investigator: Fang Yu and Vankee Lin

The purpose of this blinded, 2×2 factorial design RCT is to examine the efficacy and synergistic effect of 6- month cycling and Speed of Processing (SOP) training on cognition and relevant mechanisms [aerobic fitness, cortical thickness, and functional connectivity in default mode network (DMN)] in older adults with aMCI.

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