Efficacy and Mechanisms of Combined Aerobic Exercise and Cognitive Training in MCI (The ACT Trial)
|Dates:||9/15/2017 - 5/31/2022|
|Role:||Mary G Carey, PhD, RN, FAHA, FAAN : Co-Investigator|
|Principal Investigator:||Fang Yu and Vankee Lin|
The purpose of this blinded, 2×2 factorial design RCT is to examine the efficacy and synergistic effect of 6- month cycling and Speed of Processing (SOP) training on cognition and relevant mechanisms [aerobic fitness, cortical thickness, and functional connectivity in default mode network (DMN)] in older adults with aMCI.